In 2002, the world changes forever. Every man, every boy, every mammal with a Y chromosome everywhere on Earth suddenly collapses and dies. With the loss of more than half the planet's population, the gears of society grind to a halt, and a world of women are left to pick up the pieces and try to keep civilization from collapsing entirely.

As this deluxe edition begins, we catch up on the adventures of Yorick's monkey Ampersand (whose biology may hold the key to stopping the male-killing plague) and tells the origin of Yorick's mysterious protector, Agent 355 as Yorick searches for his fiancée in Australia, with deadly results. From Australia, Yorick and his companions continue on to Japan to learn the truth behind Ampersand's abduction.

"Every man, every boy and every other mammal with a Y chromosome everywhere on Earth is dead. The gears of society grind to a halt following the loss of nearly half the planet's population, and a world of women are left to pick up the pieces and try to keep civilization from collapsing entirely. The 'gendercide,' however, is not absolutely complete. For some unknown reason, one young man named Yorick Brown and his male monkey, Ampersand, are spared....

It's 2002, and a plague of unknown origin has killed all of the male mammals on Earth-all except an amateur escape artist named Yorick Brown and his surly helper monkey, Ampersand. As the last remaining and -chromosome carriers on the planet, Yorick and his pet hold the fate of humanity in their hands. To ensure the survival of the species, they've teamed up with a gun-toting government agent and the world's premier bioengineer to discover the secret...

In the summer of 2002, a plague of unknown origin destroyed every last sperm, fetus, and fully developed mammal with a Y chromosome-with the apparent exception of one young man and his male pet. This "gendercide" instantaneously exterminated 48% of the global population, or approximately 2.9 billion men. Now, aided by the mysterious Agent 355, the last human male Yorick Brown must contend with dangerous extremists, a hoped-for reunion with a girlfriend...

In the plague-riddled years of the early twenty-first century, the inhabitants of a small village live in fear until an enigmatic stranger arrives, offering a prophetic glimpse at the Book of Destiny, and the hope of salvation.

Ten years after a virus began turning victims into monsters called Dracules, Leila Mikami is a member of the elite VIUS squad, who stand between what remains of civilization and chaos. Leila has an agenda, however; a Dracule killed both her parents and she seeks the Dragon Eye, a magic weapon that will make her the most powerful warrior in the world, in order to exact revenge.

"AD 2100: The world has been devastated by a manmade plague. Young Daisy Ogami is infected but unaffected--naturally immune. In her blood can be found a cure that will save humanity. But the remaining world powers are concerned less with preserving humanity and more with being the first nation to return to power. Unfortunately for them, Daisy has a protector, a loyal android named Itto. In a violent reimagining of the classic assassin-and-child story...

"A cosmic plague has spread, transforming everyday people into violent, monstrous kaiju. Only the Ultramega--three individuals imbued with incredible powers--hold the line against this madness. Their battles level cities and leave untold horror in their wake. Now, the final reckoning approaches for the Ultramega...but is this a war they can even win?"--Cover, page 4.

The battles against the fierce Dracules have finally come to an end. Although the humans are victorious and Mikuni City is safe for now, Leila is deployed on a secret mission. She must rendezvous with a fellow undercover agent who has infiltrated a suspected Dracule-fighting ring.